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RNA polymerase I is responsible for transcribing RNA that codes for genes that become structural components of the ribosome. Protein coding genes are transcribed into messenger RNAs (mRNAs) that carry the information from DNA to the site of protein synthesis.
This process of protein synthesis occurs in two stages - transcription and translation. Transcription When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA ...
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Mar 02, 2020 · The proteins are folded globular structures with precisely defined function and their “active sites” can be targeted with chemical compounds. The first step is to clone and express the genes of the virus proteins and grow them as protein crystals in miniature ice cube-like trays.
Protein synthesis begins with the dissociation of ribosomal subunits and assembly of a 43S PIC. Secondary structure near the 5′ cap of the mRNA could prevent ribosome association with the mRNA, whereas The translation factor eIF2 is responsible for binding Met-tRNAiMet to the 40S ribosome.
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Proteins are long chains of amino acids, and the exact sequence of the amino acids determines the final structure and function of the protein. Instructions for that sequence are encoded in genes.
A lack of structure facilitates protein synthesis ... the enzymes responsible for this task face a similar challenge. They must find the correct starting point for protein synthesis. Therefore, in ...